Why do men tend to get more severe COVID-19?

There needs to be broader study of how biological sex differences affect outcomes with COVID-19, researchers argue in a recent paper.

Though it’s still unclear exactly why, what is clear is that men are suffering worse fates than women when it comes to COVID-19, regardless of geography or age.

A variety of data from outbreaks across the world has established this, and researchers like Johns Hopkins University biologist Sabra Klein are trying to understand more.

Last month, Klein contributed to the paper in the Journal of Critical Investigations, which calls for study of sex differences in COVID-19 outcomes. The authors also argue that it should be a significant consideration for developing effective treatments and vaccines.

Here, Klein explains what the scientific community knows so far about the different outcomes between men and women who contract COVID-19:

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